Patients may lose a few pounds of weight on metformin.Metformin is the treatment of choice for type 2 diabetes because it works well, is inexpensive, and it has been around for decades.If the patient has no side effects, the dose may increase to 1000 mg with breakfast and 1000 mg with dinner.A few weeks later, the dose may increase again to 500 mg with breakfast and 1 g with dinner.After a few weeks, the dose may increase to 500 mg with breakfast and 500 mg with dinner.To avoid stomach upset, patients usually start with a very low dose (500 mg), taken with dinner.The treatment plan will differ for each patient, but a common starting regimen is listed below: Available dosage of pills include 500 mg, 850 mg, and 1000 mg. Metformin is usually taken with meals, either once or twice a day depending on the brand. Metformin primarily reduces the liver’s ability to release glucose from its stores. Metformin ER (extended release- marketed as Glucophage XR and Fortamet).Metformin hydrochloride (marketed as Glucophage, but also a common generic medication).Metformin is manufactured under several different brand names. On average, most patients find that their HbA1c levels drop by as much as 1.5% on this medication. In addition, it is sometimes used to prevent diabetes in patients who are at risk of developing the disease (though it is not FDA approved for prediabetes). Metformin is a commonly recommended initial medication for patients with type 2 diabetes who have mild to moderately uncontrolled blood glucose.
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